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Russia says it will not "cave in" to pressure, following a fresh set of US, EU and Canadian sanctions over the conflict in Ukraine.  A spokesman said Moscow regretted "that the West is yet again displaying a complete lack of interest" in resolving the crisis in south-east Ukraine.  Russia was developing "retaliatory measures", the spokesman said.  The US sanctions focused on Crimea, which was annexed by Russia in March.  US President Barack Obama signed an executive order to ban the export of goods, technology and services to Crimea, in addition to new sanctions on Russian and Ukrainian individuals and companies. Mr Obama said the move showed the US would never accept Russia's annexation of Crimea.  Similar measures agreed by the European Union earlier this week came into effect on Saturday. Canada announced its own sanctions on Crimea on Friday.  After the peninsula was annexed, pro-Russian separatists took control of parts of the Donetsk and Luhansk regions of eastern Ukraine in April, and later declared independence.  Some 4,700 people have died and another million have been displaced by fighting in recent months.  On Friday, five Ukrainian soldiers were killed in fighting - the highest death toll since the latest attempt at a ceasefire began on 9 December.  In addition to the goods, technology and services ban, US individuals or companies cannot now buy any real estate or businesses in Crimea or fund Crimean firms.